Table 1.
Target PK model | Metric | Network 1 | Network 2 | Network 3 | Network 4 | Network 5 | Network 6 |
---|---|---|---|---|---|---|---|
Tofts Ktrans | RMSE | 8.60 × 10−2 | 8.73 × 10−2 | 2.37 × 10−2 | 4.34 × 10−2 | 1.34 × 10−1 | 7.05 × 10−2 |
nRMSE | 1.28 | 1.04 | 1.02 | 0.83 | 1.26 | 0.76 | |
| |||||||
Ex-Tofts Ktrans | RMSE | 1.87 × 10−3 | 2.24 × 10−3 | 1.50 × 10−3 | 1.88 × 10−3 | 1.84 × 10−3 | 2.31 × 10−3 |
nRMSE | 0.80 | 0.95 | 0.86 | 0.94 | 0.97 | 0.93 | |
| |||||||
Ex-Tofts Vp | RMSE | 1.72 × 10−2 | 2.36 × 10−2 | 1.58 × 10−2 | 1.88 × 10−2 | 2.04 × 10−2 | 2.27 × 10−2 |
nRMSE | 0.86 | 0.81 | 1.04 | 0.90 | 0.81 | 1.38 |