Chemical properties of the cloperastine derivatives.

S. no	Compounds (molecular formula)	Formula weight	Molar refractivity cm3	Index of refraction	Density g cm−3	Polarisability cm3
1	Cloperastine (C20H24ClNO)	329.86	96.11 ± 0.3	1.566 ± 0.02	1.120 ± 0.06	38.10 ± 0.510−24
2	Derivative 1 (C19H22ClNO2)	331.83	93.10 ± 0.3	1.565 ± 0.02	1.162 ± 0.06	36.91 ± 0.510−24
3	Derivative 2 (C37H35Cl2NO2)	596.58	173.74 ± 0.3	1.615 ± 0.02	1.198 ± 0.06	68.87 ± 0.510−24
4	Derivative 3 (C40H41Cl2NO4)	670.66	191.73 ± 0.3	1.597 ± 0.02	1.192 ± 0.06	76.00 ± 0.510−24
5	Derivative 4 (C21H20ClNO)	337.84	100.65 ± 0.3	1.624 ± 0.02	1.186 ± 0.06	39.90 ± 0.510−24
6	Derivative 5 (C22H22ClNO)	351.86	105.48 ± 0.3	1.618 ± 0.02	1.168 ± 0.06	41.81 ± 0.510−24
7	Derivative 6 (C23H30N2O2)	366.49	110.04 ± 0.3	1.575 ± 0.02	1.101 ± 0.06	43.62 ± 0.510−24
8	Derivative 7 (C21H26ClNO)	343.89	100.41 ± 0.3	1.553 ± 0.02	1.097 ± 0.06	39.80 ± 0.510−24
9	Derivative 8 (C21H25ClN2O3)	388.88	105.94 ± 0.3	1.589 ± 0.02	1.237 ± 0.06	41.99 ± 0.510−24
10	Derivative 9 (C21H28ClNO)	345.90	102.13 ± 0.4	1.572 ± 0.02	1.11 ± 0.1	40.49 ± 0.510−24
11	Derivative 10 (C16H20N2)	240.34	75.91 ± 0.3	1.556 ± 0.02	1.018 ± 0.06	30.09 ± 0.510−24
12	Derivative 11 (C17H21NO)	255.35	79.56 ± 0.3	1.551 ± 0.02	1.024 ± 0.06	31.54 ± 0.510−24
13	Derivative 12 (C32H39NO2)	469.65	144.65 ± 0.4	1.590 ± 0.03	1.09 ± 0.1	57.34 ± 0.510−24
14	Derivative 13 (C18H22BrNO)	348.27	91.46 ± 0.3	1.561 ± 0.02	1.234 ± 0.06	36.25 ± 0.510−24
15	Derivative 14 (C32H39NO4)	501.65	145.86 ± 0.3	1.596 ± 0.02	1.171 ± 0.06	57.82 ± 0.510−24
16	Derivative 15 (C16H19ClN2)	274.78	80.80 ± 0.3	1.565 ± 0.02	1.107 ± 0.06	32.03 ± 0.510−24
17	Derivative 16 (C17H22N2O)	270.36	81.86 ± 0.3	1.554 ± 0.02	1.043 ± 0.06	32.45 ± 0.510−24
18	Derivative 17 (C22H29N3O4S)	431.54	117.69 ± 0.3	1.598 ± 0.02	1.252 ± 0.06	46.65 ± 0.510−24
19	Derivative 18 (C25H27ClN2)	390.94	118.03 ± 0.3	1.617 ± 0.02	1.159 ± 0.06	46.79 ± 0.510−24
20	Derivative 19 (C13H22N4O3S)	314.40	85.64 ± 0.3	1.558 ± 0.02	1.184 ± 0.06	33.95 ± 0.510−24
21	Derivative 20 (C19H28N2O4)	348.43	95.66 ± 0.3	1.532 ± 0.02	1.130 ± 0.06	37.92 ± 0.510−24
22	Derivative 21 (C15H24N4S)	292.44	84.56 ± 0.4	1.614 ± 0.03	1.20 ± 0.1	33.52 ± 0.510−24
23	Derivative 22 (C13H15ClN4O)	278.73	75.19 ± 0.3	1.662 ± 0.02	1.371 ± 0.06	29.80 ± 0.510-24
24	Derivative 23 (C21H23NO3)	337.41	99.62 ± 0.3	1.640 ± 0.02	1.221 ± 0.06	39.49 ± 0.510−24
25	Derivative 24C21H25N3O2S	383.50	110.15 ± 0.5	1.652 ± 0.05	1.27 ± 0.1	43.66 ± 0.510−24
26	Derivative 25 (C22H23ClN2O2)	382.88	105.85 ± 0.3	1.614 ± 0.02	1.261 ± 0.06	41.96 ± 0.510−24
27	Derivative 26 (C19H19ClN2)	310.82	90.05 ± 0.3	1.625 ± 0.02	1.221 ± 0.06	35.69 ± 0.510−24
28	Derivative 27 (C20H24N2)	292.41	92.23 ± 0.3	1.587 ± 0.02	1.065 ± 0.06	36.56 ± 0.510−24
29	Derivative 28 (C26H34N2O3)	422.55	123.24 ± 0.3	1.555 ± 0.02	1.101 ± 0.06	48.85 ± 0.510−24
30	Derivative 29 (C22H22N2O)	330.42	100.29 ± 0.4	1.641 ± 0.03	1.18 ± 0.1	39.75 ± 0.510−24
31	Derivative 30 (C9H16N6S)	240.32	66.09 ± 0.5	1.645 ± 0.05	1.31 ± 0.1	26.20 ± 0.510−24
32	Derivative 31 (C16H18N2O2)	270.32	76.43 ± 0.3	1.613 ± 0.02	1.231 ± 0.06	30.30 ± 0.510−24
33	Derivative 32 (C14H17ClN4S)	308.82	85.45 ± 0.5	1.645 ± 0.05	1.31 ± 0.1	33.87 ± 0.510−24
34	Derivative 33 (C8H15N7O2S3)	337.44	79.06 ± 0.5	1.808 ± 0.05	1.83 ± 0.1	31.34 ± 0.510−24
35	Derivative 34 (C14H16ClN3O)	277.74	77.10 ± 0.3	1.655 ± 0.05	1.332 ± 0.06	30.56 ± 0.510−24
36	Derivative 35 (C17H20N2S)	284.41	87.81 ± 0.3	1.615 ± 0.02	1.131 ± 0.06	34.81 ± 0.510−24