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Study design of the pivotal phase 3 clinical trials (ZOE-50 and ZOE-70) and current long-term follow-up study. #Pre-vaccination blood sample and 2 RZV doses 2 months apart. *Collected from subsets of participants for humoral and cell-mediated immunity assessment. Abbreviations: RZV, adjuvanted recombinant zoster vaccine; ZOE-50, pivotal phase 3 clinical trial of RZV in adults aged ≥50 years; ZOE-70, pivotal phase 3 clinical trial of RZV in adults aged ≥70 years.
