Table 1. Demographic features, underlying conditions, and pre-diagnosis medications among patients with vulvovaginal candidiasis, recurrent vulvovaginal candidiasis, and females with an outpatient gynecologic visit.
| VVC | RVVC | Females with an outpatient gynecologic visit in 2018 | ||||
|---|---|---|---|---|---|---|
| n = 149,934 | % | n = 3,689 | % | n = 2,743,624 | % | |
| Median age, years (range) | 34 | (0–102) | 34 | (1–95) | 42 | (0–98) |
| Age group, years | ||||||
| 0–17 | 9,297 | 6.2% | 69 | 1.9% | 26,017 | 0.9% |
| 18–34 | 66,250 | 44.2% | 1,853 | 50.2% | 860,892 | 31.4% |
| 35–44 | 30,946 | 20.6% | 797 | 21.6% | 625,190 | 22.8% |
| 45–54 | 24,654 | 16.4% | 577 | 15.6% | 658,572 | 24.0% |
| 55–64 | 15,546 | 10.4% | 320 | 8.7% | 532,663 | 19.4% |
| ≥65 | 3,241 | 2.2% | 73 | 2.0% | 40,200 | 1.5% |
| U.S. Census region of primary beneficiary’s residence | ||||||
| Northeast | 25,231 | 16.8% | 727 | 19.7% | 589,363 | 21.5% |
| Midwest | 26,987 | 18.0% | 639 | 17.3% | 507,676 | 18.5% |
| South | 77,595 | 51.8% | 1,952 | 52.9% | 1,322,200 | 48.2% |
| West | 19,814 | 13.2% | 363 | 9.8% | 321,807 | 11.7% |
| Missing | 307 | 0.2% | 8 | 0.2% | 2,578 | 0.1% |
| Conditions on or in the 30 days before the index date | ||||||
| Diabetes | 9,979 | 6.7% | 394 | 10.7% | 63,980 | 2.3% |
| Pregnancy | 2,794 | 1.9% | 44 | 1.2% | 9,779 | 0.4% |
| Hematologic malignancy | 171 | 0.1% | 4 | 0.1% | 2,809 | 0.1% |
| HIV | 102 | 0.1% | 8 | 0.2% | 1,001 | 0.1% |
| Transplant | 78 | 0.1% | 2 | 0.1% | 1,579 | 0.0% |
| Medications prescribed in the 30 days before the index date | ||||||
| Systemic antibacterial medications | 25,738 | 17.2% | 561 | 15.2% | 195,447 | 7.1% |
| Aminoglycoside | 19 | 0.1% | 1 | 0.2% | 178 | 0.1% |
| Beta-lactam | 9 | 0.0% | 0 | 0.0% | 29 | 0.0% |
| Cephalosporin | 4,595 | 17.9% | 80 | 14.3% | 26,524 | 13.6% |
| Chloramphenicol & combination | 0 | 0.0% | 0 | 0.0% | 0 | 0.0% |
| Clindamycin | 1,077 | 4.2% | 32 | 5.7% | 7,638 | 3.9% |
| Erythromycin/macrolide | 3,815 | 14.8% | 118 | 21.0% | 42,845 | 21.9% |
| Penicillins | 10,441 | 40.6% | 173 | 30.8% | 65,509 | 33.5% |
| Tetracyclines | 2,884 | 11.2% | 84 | 15.0% | 27,349 | 14.0% |
| Sulfonamide & combination | 2,829 | 11.0% | 64 | 11.4% | 18,265 | 9.3% |
| Urinary anti-infectives | 3,434 | 13.3% | 89 | 15.9% | 21,756 | 11.1% |
| Metronidazole | 3,894 | 2.6% | 155 | 4.2% | 10,720 | 0.4% |
| Steroids | 6,654 | 4.4% | 179 | 4.9% | 83,334 | 3.0% |
| Estrogen-containing contraceptives | 15,992 | 10.7% | 480 | 13.0% | 268,512 | 9.8% |
| Hormone replacement therapy | 2,734 | 1.8% | 90 | 2.4% | 50,912 | 1.9% |
| Progestin-only contraceptives | 1,479 | 1.0% | 45 | 1.2% | 27,251 | 1.0% |