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. 2020 Feb 4;10(10):5610–5635. doi: 10.1039/c9ra09510a

List of 1,2,3-triazolyl compounds possessing anti-viral activity as observed using IC50 and EC50 values.

Sr. no. Parent compound Biological target Anti-virus Reference
60 graphic file with name c9ra09510a-u60.jpg EC50 (μM) 10
TK + VZV 3.62
TK − VZV 7.85
61 graphic file with name c9ra09510a-u61.jpg IC50 (nM) 99
HIV-1 proteases (wt) 6 ± 0.5
62 graphic file with name c9ra09510a-u62.jpg IC50 (nM) 102
HIV-1 proteases (6X) 15.7
63 graphic file with name c9ra09510a-u63.jpg EC50 (μM) 103
IIIB 0.020
E138K 0.014
64 graphic file with name c9ra09510a-u64.jpg IC50 (μM) 104
HIV-1 NL4–3 7.0 ± 0.8
65 graphic file with name c9ra09510a-u65.jpg IC50 (μM) 105
H9 cells 0.01