Skip to main content
. 2020 Feb 4;10(10):5610–5635. doi: 10.1039/c9ra09510a

List of 1,2,3-triazolyl pharmacophore molecules possessing anti-diabetic activity as observed using IC50 values.

Sr. no. Parent compound Biological target Anti-diabetic Reference
69 graphic file with name c9ra09510a-u69.jpg IC50 (μM) 111
α-Glucosidase 0.8 ± 0.01
70 graphic file with name c9ra09510a-u70.jpg IC50 (μM) 113
α-Glucosidase 181.0 ± 1.4
71 graphic file with name c9ra09510a-u71.jpg IC50 (μM) 114
α-Glucosidase 2.06
72 graphic file with name c9ra09510a-u72.jpg IC50 (μg mL−1) 115
HepG2 72.19
73 graphic file with name c9ra09510a-u73.jpg IC50 (μM ± SEM) 116
α-Glucosidase 72.71 ± 1.09