Table 3. False positive rate.
Solid tumor Mutations | Number of Mutations Detected | False Positive | |||
1% | 0.50% | 0.125% | 0% | ||
A | 50ng | 37(100%) | 36(97%) | 26(70%) | 0(0%) |
10ng | 37(100%) | 36(97%) | 23(62%) | 1(3%) | |
B | 50ng | 38(100%) | 38(100%) | 38(100%) | 0(0%) |
10ng | 38(100%) | 38(100%) | 33(87%) | 0(0%) | |
C | 50ng | 38(100%) | 37(97%) | 34(89%) | 1(3%) |
10ng | 38(100%) | 37(97%) | 23(61%) | 0(0%) | |
* D | 50ng | 5(100%) | 5(100%) | 4(80%) | 1(20%) |
10ng | 5(100%) | 5(100%) | 2(40%) | 0(0%) | |
E | 50ng | 37(100%) | 36(97%) | 36(97%) | 4(11%) |
10ng | 37(100%) | 35(95%) | 19(51%) | 1(3%) | |
Myeloid Mutations | Number of Mutations Detected | False Positive | |||
1% | 0.50% | 0.13% | 0% | ||
A | 50ng | 15(94%) | 15(94%) | 4(25%) | 0(0%) |
10ng | 15(94%) | 13(81%) | 4(25%) | 0(0%) | |
B | 50ng | 17(100%) | 17(100%) | 17(100%) | 0(0%) |
10ng | 17(100%) | 17(100%) | 11(65%) | 0(0%) | |
C | 50ng | 16(94%) | 15(88%) | 8(47%) | 0(0%) |
10ng | 16(94%) | 15(88%) | 1(6%) | 0(0%) | |
E | 50ng | 17(100%) | 17(100%) | 17(100%) | 6(35%) |
10ng | 17(100%) | 17(100%) | 12(71%) | 2(12%) |
*5 reference mutations were covered by the assay