Fig. 7. In vivo wound healing experiments. (A) Skin defects of a rabbit and application of PU-PAAm hydrogels; (B) visual inspection of the healings skin surface after surgery; (C) quantitative analysis of skin healing after surgery (***p < 0.001, **p < 0.01, *p < 0.05); (D) traces of wound-bed closure for each treatment; (E) defected skin tissue with HE and Masson staining after 3, 9, 17 days, respectively.