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. 2001 May;45(5):1511–1514. doi: 10.1128/AAC.45.5.1511-1514.2001

TABLE 2.

MIC50s, MIC90s, and geometric mean MICs of four antibiotics for S. milleri groupab

Drug and parameter μg/ml
S. intermedius S. constellatus S. anginosus
Penicillin
 MIC50 0.06 0.06 0.06
 MIC90 0.06 0.25 0.25
 Mean 0.037 0.089 0.049
Ampicillin
 MIC50 0.12 0.25 0.12
 MIC90 0.25 0.5 0.25
 Mean 0.14 0.23 0.078
Ceftriaxone
 MIC50 0.06 0.25 0.25
 MIC90 0.12 0.5 0.5
 Mean 0.079 0.23 0.16
Clindamycin
 MIC50 0.03 0.06 0.06
 MIC90 0.25 0.25 16
 Mean 0.060 0.053 0.21
a

Differences in MICs of beta-lactam antibiotics for the three species were significant (P < 0.05), but differences in MICs of clindamycin were not (P = 0.09) (Kruskal-Wallis test). 

b

MIC of penicillin for S. constellatus was greater than that for S. intermedius; MIC of ampicillin for S. constellatus was greater than that for S. anginosus; MICs of ceftriaxone for S. constellatus and for S. anginosus were greater than that for S. intermedius; P < 0.05 for all comparisons (Mann-Whitney test).