Toxicity profile of the target compounds using Toxicity Prediction of preADMET protocol.
| Molecule | 4 | 5 | 6 | Sach A |
|---|---|---|---|---|
| Algae_at | 0.0255 | 0.0215 | 0.015 | 0.016 |
| Ames_test | Mutagen | Mutagen | Mutagen | Mutagen |
| Carcino_Mouse | Positive | Positive | Negative | Positive |
| Carcino_Rat | Negative | Positive | Positive | Positive |
| Daphnia_at | 0.0485 | 0.024 | 0.021 | 0.022 |
| hERG_inhibition | Medium risk | Medium risk | Medium risk | Medium risk |
| Medaka_at | 0.005 | 0.001 | 0.001 | 0.001 |
| Minnow_at | 0.019 | 0.003 | 0.003 | 0.003 |
| TA100_10RLl | Positive | Negative | Positive | Negative |
| TA100_NA | Negative | Negative | Negative | Negative |
| TA1535_10RLl | Negative | Negative | Negative | Negative |
| TA1535_NA | Negative | Negative | Negative | Negative |