TABLE 4.
Mutations in acrR
| Isolate | AcrA expression | DNA position | Codon substitution | No. of silent mutationsa |
|---|---|---|---|---|
| CH5 | + | 9188 (ACC→AAC) | T5N | 3 |
| CH10 | + | 9209 (ACG→ATG) | T12M | 4 |
| 9812 (ACT→ATT) | T213I | |||
| 9815 (AAC→ACC) | N214T | |||
| CH15 | + | 9516 (CCA→CTA) | H115Y | 2 |
| CH19 | + | Δ 9 nt (9383–9391)b | IGEL (70–73)→Y | |
| CH21 | + | None | 0 | |
| CH24 | + | None | 3 | |
| CH27 | + | 22-nt duplication (9715–9736) | FAPQSFDL (78–86) repeated, creating a frameshift | 1 |
| CH29 | + | 9256 (GGG→AGG) | G28R | 0 |
a
Changes in nucleotide sequence, with no change in amino acid.
b
nt, nucleotide.