TABLE 5.
Restoration of sensitivity to select antibiotics in clinical E. coli strains complemented with wild-type acrR
| Strain | MIC (μg/ml)a
|
||
|---|---|---|---|
| Tetracycline | Chloramphenicol | Norfloxacin | |
| CH5 | 83 | 253 | 194 |
| CH5(pHRPacrR) | 27 | 73 | 138 |
| CH10 | 258 | 258 | 250 |
| CH10(pHRPacrR) | 81 | 103 | 78 |
| CH19 | ND | ND | 51 |
| CH19(pHRPacrR) | ND | ND | 18 |
| CH27 | 44 | 8 | 236 |
| CH27(pHRPacrR) | 20 | 2 | 146 |
| CH29 | 75 | 275 | 117 |
| CH29(pHRPacrR) | 56 | 80 | 21 |
a
All susceptibilities were determined using gradient plates. ND, not done, since these strains were already relatively sensitive to tetracycline and chloramphenicol.