Fig. 2. CircBANP knockdown suppressed the proliferation, migration, invasion, and enhanced the apoptosis in GC cells. (A) MKN-74 and MKN-45 cells were transfected with si-NC, si-circBANP-1, si-circBANP-2 or si-circBANP-3 for 48 h, and then circBANP expression was detected by qRT-PCR. MKN-74 and MKN-45 cells were transfected with si-NC or si-circBANP-1, followed by the determination of cell proliferation by CCK-8 assay after 0, 24, 48 and 72 h transfection (B and C), cell colony formation using a standard colony formation assay 14 days after transfection (D), cell apoptosis by flow cytometry after 48 h transfection (E), cell migration (F) and invasion (G) by transwell assay after 24 h transfection. *P < 0.05 vs. si-NC.