Fig. 1. (A) The mRNA expression levels of BMP-9 in lung cancer tissues and adjacent normal tissues; (B and C) BMP-9 recombinant protein promoted the A549 (B) and NCl-H1650 (C) cells proliferation in CCK-8 assay; (D–F) BMP-9 recombinant protein up-regulated p-Smad1/5 level and PI3K/Akt pathway. Data were represented as the mean ± SEM, ***p < 0.001 versus adjacent normal tissues, #p < 0.05 versus control group, ##p < 0.01 versus control group; ##p < 0.001 versus control group.
