Affinity constant (KD) between DTX-1 and selected aptamers.
| Clone no. | Family | Aptamer sequence | K D a (μM) |
|---|---|---|---|
| N11 | A | GAGGCAGCACTTCACACGATCGGACCCAAACTTTACCTTACCCCCATCTGCGTAATGACTGTAGTGATG | 0.498 |
| N26 | B | GAGGCAGCACTTCACACGATGCCTCCTACCCTGCTGCCTTAGCCGGTCTGCGTAATGACTGTAGTGATG | NB |
| N16 | C | GAGGCAGCACTTCACACGATATTTGGGGATCAGCCAGGTCAGTGCCACTGCGTAATGACTGTAGTGATG | 0.729 |
| N50 | D | GAGGCAGCACTTCACACGATCGTCCCTGCCCCTGCCTCCTTTCTATGCTGCGTAATGACTGTAGTGATG | 2.57 |
| N29 | E | GAGGCAGCACTTCACACGATCGCTGAAGTCAACCTCCCCTACCTGTGCTGCGTAATGACTGTAGTGATG | 2.2 |
| N59 | F | GAGGCAGCACTTCACACGATCCACCAGGCCAAACACGACCCCAAACACTGCGTAATGACTGTAGTGATG | 0.17 |
| N63 | G | GAGGCAGCACTTCACACGATTCCCTCCTCCTTTATATCCGGTCCGATCTGCGTAATGACTGTAGTGATG | 0.9 |
| N72 | H | GAGGCAGCACTTCACACGATCCCCGTTCCTTGTCCCCTTCTCTATATCTGCGTAATGACTGTAGTGATG | NB |
| N41 | I | GAGGCAGCACTTCACACGATCCCCCCCACACTCTTCCAACCCCCTCTCTGCGTAATGACTGTAGTGATG | 1890 |
| N8 | J | GAGGCAGCACTTCACACGATCACGGCAGGAGACCATCACCATTATCGCTGCGTAATGACTGTAGTGATG | NB |
a
NB: no binding.