Table 1. Chronological age prediction and correlation with methylome-wide entropy.
Clock type | DNAmAge name | Tissue | r with age (n = 339)* | Age prediction median error | r with entropy(n = 339)*, † |
---|---|---|---|---|---|
Standard clocks | DNAmAge | Pan | 0.89 | 0.12 | 0.43 |
Liver | 0.92 | 0.10 | 0.40 | ||
Developmental clocks | dev.DNAmAge | Pan | 0.87 | 0.14 | 0.39 |
Liver | 0.91 | 0.12 | 0.37 | ||
Interventional clocks | int.DNAmAge | Pan | 0.85 | 0.17 | 0.29 |
Liver | 0.86 | 0.15 | 0.47 |
p<0.0001.
Methylome-wide entropy calculated from ~28K CpGs.