Skip to main content
. 2022 Mar 29;11:e75374. doi: 10.7554/eLife.75374

Appendix 2—figure 2. Mendelian randomization estimates for genetically predicted effects of GrimAge and PhenoAge acceleration on multiple cancer subtypes.

Appendix 2—figure 2.

Odds ratios and 95% confidence intervals are reported per 1 year increase in (A) GrimAge acceleration, (B) PhenoAge acceleration. GrimAge and PhenoAge acceleration were instrumented by four and 11 genetic variants, respectively. Results were obtained using inverse variance weighted MR (dark blue), weighted median (sky blue) and weighted mode (turquoise) methods. Data sources: BCAC, OCAC, CIMBA, PRACTICAL, ILCCO and GECCO.