Figure 6. Mendelian randomization estimates for genetically predicted effects of GrimAge acceleration on parental history of multiple cancers.
Odds ratios and 95% confidence intervals are reported per 1 year increase in GrimAge acceleration. GrimAge acceleration was instrumented by four genetic variants. Results were obtained using inverse variance weighted MR (dark blue), weighted median (sky blue) and weighted mode (turquoise) methods. Data source: UK Biobank.