Figure 6.

CISD2 expression is correlated with immune infiltration and cumulative survival in glioma with TIMER. (a) CISD2 expression shows a notably inverse correlation with macrophages and no correlation with B cells, CD8⁺ T cells, CD4⁺ T cells, neutrophils, and DCs in GBM. Meanwhile, CISD2 expression is notably positively correlated with B cells, CD8⁺ T cells, and neutrophils and negatively correlated with CD4⁺ T cells in LGG. (b) The Kaplan-Meier curves analyses of immune cell infiltration and CISD2 expression in GBM and LGG. GBM: glioblastoma multiforme; LGG: low-grade glioma.