Figure 2.

Predicted tumor size and weight (a) There is no significant difference in tumor growth among all mice. (b) TGF-β1 gene knockout mice and mice injected with additional TGF-β develop larger and more severe tumors than wild-type mice, while the injection of 1D11 leads to reduced tumor growth. (c) There is no significant difference in tumor growth rate between the TGF-β1 knockout group and the wild-type mice, while the tumors in mice injected with additional TGF-β are larger and heavier. The tumors in mice treated with 1D11 have reduced size and weight compared to those in wild-type mice. (d) In comparison to wild-type mice, the tumors in the gene knockout mice and 1D11-treated mice are smaller, while the tumors in mice treated with additional TGF-β develop more rapidly.