Proliferation inhibition to MDA-MB-231 cells and MDA-MB-231/DOX cells (n = 3)a.
Compounds | IC50 (μM, mean ± SEM) | |
---|---|---|
To MDA-MB-231 cells | To MDA-MB-231/DOX cells | |
DOX | 0.3990 ± 0.0322 | 5.3110 ± 0.0714 |
DOX/AS | 0.2776 ± 0.0039 | 1.9840 ± 0.0497 |
LPs-DOX/AS | 0.2388 ± 0.0077* | 1.0310 ± 0.0012* |
R8-LPs-DOX/AS | 0.2163 ± 0.0034** | 0.9019 ± 0.0077** |
FA-R8-LPs-DOX/AS | 0.1846 ± 0.0083** | 0.3279 ± 0.0045** |
*P < 0.05, **P < 0.01, compared with DOX/AS group.