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. 2020 Mar 20;10(20):11573–11581. doi: 10.1039/c9ra09040a

Proliferation inhibition to MDA-MB-231 cells and MDA-MB-231/DOX cells (n = 3)a.

Compounds IC50 (μM, mean ± SEM)
To MDA-MB-231 cells To MDA-MB-231/DOX cells
DOX 0.3990 ± 0.0322 5.3110 ± 0.0714
DOX/AS 0.2776 ± 0.0039 1.9840 ± 0.0497
LPs-DOX/AS 0.2388 ± 0.0077* 1.0310 ± 0.0012*
R8-LPs-DOX/AS 0.2163 ± 0.0034** 0.9019 ± 0.0077**
FA-R8-LPs-DOX/AS 0.1846 ± 0.0083** 0.3279 ± 0.0045**
a

*P < 0.05, **P < 0.01, compared with DOX/AS group.