Table 1.
Demographics and baseline characteristics (avacopan, N = 7)
| Characteristics | Values |
|---|---|
| Age (years), mean ± SD [range] | 44.1 ± 13.2 [25–59] |
| Sex (female/male), n/n | 4 / 3 |
| Race (White/Asian), n/n | 6 / 1 |
| Body mass index (kg/m2), mean ± SD | 30.1 ± 8.3 |
| Time since biopsy diagnosis (months), median (range) | 15.4 (1–42) |
| UPCR (mg/g), geometric mean (range) | 1801 (1181–3392) |
| UACR (mg/g), geometric mean (range) | 1425 (922–2898) |
| eGFR (mL/min/1.73 m2), mean ± SD | 65.9 ± 18.1 |
| Urinary MCP-1:creatinine ratio (pg/mg), geometric mean (range) | 514 (225–975) |
| Urinary RBC count (cells/high power field), geometric mean (range) | 6.21 (1.22–61.24) |
| Urinary EGF:MCP-1 ratio (pg/pg), geometric mean (range) | 15.14 (6.95–49.09) |
| Serum IgA:plasma C3 ratio (mg/mg), geometric mean (range) | 2.96 (2.21–4.81) |