Table 2.

Cox regression analysis of prognostic factors in prospective cohort

Variable	Univariate analysis		Multivariate analysis
	HR (95% CL)	P-value	HR (95% CL)		P-value
RF scorea	1.110 (1.046–1.178)	5.93 × 10−4	1.088 (1.010–1.173)		0.0271
Agea	1.039 (1.011–1.069)	7.18 × 10−3	1.020 (0.989–1.053)		0.2122
WHO gradeb		4.52 × 10−5			0.2390
III versus II	1.751 (0.503–6.096)	0.3788	0.900 (0.215–3.759)		0.8847
IV versus II	6.949 (2.624–18.397)	9.53 × 10−5	2.158 (0.600–7.766)		0.2390
IDH1 statusb Mutant versus wild-type	0.115 (0.050–0.269)	5.71 × 10−7	0.209 (0.079–0.553)		0.0016
1p/19q statusb Cod versus Non-Cod	0.020 (3.69 × 10−4–1.038)	0.0522

Cod = co-deletion

^a Numerical variables.

^b Categorical variables.