Table 1.

Analysis of covariance looking at the overall effect of the combined BMI/WHR group on the volumes of subcortical regions-of-interest before and after adjustment for total GM volume.

Region of interest	Hemisphere	Results adjusted for covariates				Results adjusted for GM atrophy and covariates
		F (5, 15,619)	p value	ηp2		F (5, 15,619)	p value	ηp2
Thalamus	Left	6.618	3.658 × 10−6	0.002	*	4.461	4.606 × 10−4	0.001	*
Thalamus	Right	7.056	1.345 × 10−6	0.002	*	4.921	1.672 × 10−4	0.001	*
Caudate	Left	5.98	1.559 × 10−5	0.001	*	5.235	8.306 × 10−5	0.001	*
Caudate	Right	6.943	1.741 × 10−6	0.002	*	6.164	1.027 × 10−5	0.002	*
Putamen	Left	2.752	0.017	0.001		1.695	0.131	5.43 × 10−4
Putamen	Right	2.668	0.02	8.542 × 10−4		1.478	0.193	0.0004
Pallidum	Left	7.238	8.838 × 10−7	2.314 × 10−3	*	7.24	8.798 × 10−7	2.315 × 10−4	*
Pallidum	Right	10.244	8.074 × 10−10	0.003	*	9.356	6.489 × 10−9	0.002	*
Amygdala	Left	2.751	0.017	8.81 × 10−4		2.733	0.018	0.001
Amygdala	Right	3.804	0.001	0.001	*	3.626	0.0028	0.001	*
Nucleus accumbens	Left	8.4318	5.606 × 10−8	0.002	*	4.886	1.805 × 10−4	0.001	*
Nucleus accumbens	Right	9.884	1.882 × 10−9	0.003	*	5.676	3.098 × 10−5	0.001	*
Hippocampus	Left	0.927	0.461	2 × 10−3		0.586	0.071	1.88
Hippocampus	Right	2.546	0.026	0.001		2.563	0.025	0.001

P values in bold, and marked with *, are those significant after Bonferroni correction at p value 0.004.