Table 3.
Partial correlations between indicators of body composition derived from abdominal MRI and neuroimaging outcomes adjusted for covariates.
Abdominal MRI | Brain MRI | r | CI 95% | Adjusted variance explained | p value | Significant |
---|---|---|---|---|---|---|
Visceral adipose tissue volume | Brain volume | −0.072 | [−0.1, −0.05] | 0.00486 | 1.928 × 10−07 | * |
GM volume | −0.096 | [−0.12, −0.07] | 0.00888 | 4.279 × 10−12 | * | |
WM volume | 0.023 | [0.05, 0.0] | 0.00018 | 0.085 | ||
Global efficiency | −0.011 | [−0.02, 0.04] | 0.00031 | 0.441 | ||
Local efficiency | −0.018 | [−0.01, 0.05] | 0.0001 | 0.217 | ||
Abdominal subcutaneous adipose tissue volume | Brain volume | −0.067 | [−0.09, −0.04] | 0.00419 | 0.000001 | * |
GM volume | −0.094 | [−0.12, −0.07] | 0.0085 | 1.178 × 10−11 | * | |
WM volume | −0.018 | [−0.05, 0.01] | 0.00004 | 0.184 | ||
Global efficiency | 0.015 | [−0.01, 0.05] | 0.00019 | 0.289 | ||
Local efficiency | 0.01 | [−0.02, 0.04] | 0.00034 | 0.498 | ||
Total adipose tissue volume | Brain volume | −0.112 | [−0.13, −0.09] | 0.012 | 2.679 × 10−21 | * |
GM volume | −0.08 | [−0.1, −0.06] | 0.00614 | 1.157 × 10−11 | * | |
WM volume | −0.021 | [−0.04, 0.0] | 0.00016 | 0.075 | ||
Global efficiency | 0.006 | [−0.02, 0.03] | 0.00028 | 0.649 | ||
Local efficiency | 3E-04 | [−0.02, 0.02] | 0.0003 | 0.979 | ||
Lean tissue volume (normalized by body weight) | Brain volume | 0.048 | [0.03, 0.07] | 0.002 | 0.00004 | * |
GM volume | 0.046 | [0.02, 0.07] | 0.001878 | 0.000093 | * | |
WM volume | 0.032 | [0.01, 0.06] | 0.000762 | 0.0065 | * | |
Global efficiency | 0.005 | [−0.02, 0.03] | 0.000283 | 0.649 | ||
Local efficiency | 3E−04 | [−0.02, 0.02] | 0.000316 | 0.979 |
Significant results, at the p = 0.05 level, are shown in bold and with *.