Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Apr 28;13:2303. doi: 10.1038/s41467-022-29433-y

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 2 — a Retinal development. Model simulations of ON and OFF retinal ganglion cells (red and blue circles) from the contralateral and ipsilateral eyes (high and low contrast). b Receptive fields (RF) of 64 thalamic afferents receiving input from the retinas illustrated in a and thalamic afferent sampling density (16 receptive fields sampling the same visual point). c Model simulations of the afferent sorting in the cortical subplate. The 64 afferents (Aff.) illustrated in b are sorted first by retinotopy (left), then by eye input (middle) and then by ONOFF polarity (right). d Model simulations of the eye-polarity grid after the afferent axon arbors spread and combine in each cortical pixel (red: ON dominated, blue: OFF dominated, black line: border between regions dominated by contralateral and ipsilateral eyes). e Model simulations of the eye-polarity grid in a larger cortical patch. f Primordial orientation maps for the contralateral (left) and ipsilateral eyes (right) resulting from thalamocortical convergence. g Adult orientation map after the primordial map is optimized by visual experience.