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. 2022 Apr 28;13:2229. doi: 10.1038/s41467-022-29488-x

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — Participant numbers at each stage are shown in the figure. * Patients judged as potential participants for the trial, including some (n = 329) identified through remote review of electronic patient records by researchers followed by “cold call” and others identified at clinical team meetings. ¥ Attendance of at least the first 3 days of allocated treatment (HARPdoc or BGAT) plus at least one 1:1 session for HARPdoc was considered as “received allocated treatment”.