. Author manuscript; available in PMC: 2023 May 1.

Published in final edited form as: Clin Exp Allergy. 2022 Jan 16;52(5):658–669. doi: 10.1111/cea.14091

TABLE 2.

Characteristics of subjects with available methylation data with their asthma status at ages 10, 18, and 26 years stratified by sex in the IOW cohort.

Factors	Data for asthma acquisition during adolescence			Data for asthma acquisition during young adulthood
Factors	Whole cohort	Analytical sample	p-value	Whole cohort	Analytical sample	p-value
Males	n=328	n=187		n=329	n=186
SES^#	n (%)	n (%)	0.48	n (%)	n (%)	0.35
High	33 (10.06)	16 (8.56)		32 (9.73)	15 (8.06)
Middle	247 (75.3)	142 (75.94)		248 (75.38)	141 (75.81)
Low	39 (11.89)	27 (14.44)		39 (11.85)	28 (15.05)
Missing	9 (2.74)	2 (1.07)		10 (3.04)	2 (1.08)
Secondhand smoke^$			0.85			0.88
Yes	112 (34.15)	68 (36.36)		115 (34.95)	68 (36.56)
No	181 (55.18)	101 (54.01)		180 (54.71)	101 (54.3)
Missing	35 (10.67)	18 (9.63)		34 (10.33)	17 (9.14)
	Mean±SD	Mean±SD		Mean±SD	Mean±SD
BMI at age 10 years	17.56±2.49	17.67±2.59	0.59	17.53±2.42	17.64±2.47	0.55
	Median (MAD)	Median (MAD)		Median (MAD)	Median (MAD)
Breastfeeding^¥ (weeks)	12 (12)	12.5 (12.5)	0.31	12 (11.5)	12 (12)	0.35
Females	n=405	n=249		n=391	n=239
SES	n (%)	n (%)	0.63	n (%)	n (%)	0.39
High	39 (9.63)	25 (10.04)		38 (9.72)	25 (10.46)
Middle	300 (74.07)	192 (77.11)		292 (74.68)	186 (77.82)
Low	59 (14.57)	30 (12.05)		54 (13.81)	27 (11.30)
Missing	7 (1.73)	2 (0.80)		7 (1.79)	1 (0.42)
Secondhand smoke			0.20			0.19
Yes	144 (35.56)	74 (29.72)		135 (34.53)	68 (28.45)
No	212 (52.35)	136 (54.62)		208 (53.2)	133 (55.65)
Missing	49 (12.10)	39 (15.66)		48 (12.28)	38 (15.9)
	Mean±SD	Mean±SD		Mean±SD	Mean±SD
BMI at age 10 years	18.58±3.08	18.49±2.97	0.99	18.5±3	18.41±2.87	0.66
	Median (MAD)	Median (MAD)		Median (MAD)	Median (MAD)
Breastfeeding (weeks)	11.5 (11.5)	12 (12)	0.56	11.5 (11.5)	12 (12)	0.59

^#:

SES refers to socioeconomic status in childhood.

^$:

Participants got secondhand smoke before age 10 years.

^¥:

The length of time for breastfeeding.