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Reaction conditions: quinolinyl-alkylated ketone, 1b (0.5 mmol), Cu(OAc)2 (10 mol%), TEMPO (0.1 mmol) and 2,2′-bipyridyl (0.1 mmol), in TBAA (1 eq.) at 80 °C for 1 h, sequential addition of isatin, 2 (0.5 mmol), l-proline 3a or sarcosine 3b (0.6 mmol) at 80 °C for another 1 h.
Isolated yields.
