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. 2022 Feb 28;47(3):419–429. doi: 10.1007/s13318-021-00745-6

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License, which permits any non-commercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by-nc/4.0/.

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Fig. 4 — Mean (SD) plasma concentrations of abrocitinib and metabolites prior to dosing on Days 1–4, and at 24 h following dosing on Day 4 following 4 days of abrocitinib 200 mg once-daily dosing to assess the steady state of abrocitinib M1, M2, and M4