Table 2.
Medication use at any time point prior to echocardiogram, according to diastolic function groups.
| Normal= 538 N (%) | Indeterminate = 118 N (%) | DD = 150 N (%) | P-value | |
|---|---|---|---|---|
| Immune Medications (ever use) | ||||
| Mycophenolate mofetil | 160/537 (30) | 27/116 (23) | 20/148 (14) | <0.001 |
| Methotrexate | 96/537 (18) | 9 (8) | 18/148 (12) | 0.010 |
| Hydroxychloroquine | 132/537 (25) | 20 (17) | 22/148 (15) | 0.016 |
| Cyclophosphamide | 38/537 (7) | 8 (7) | 6/148 (4) | 0.41 |
| Azathioprine | 21/536 (4) | 7/117 (6) | 6/148 (4) | 0.60 |
| Prednisone | 168/536 (31) | 53 (45) | 49/148 (33) | 0.018 |
| Cardiovascular Medications (ever use) | ||||
| Beta blocker | 57/461 (12) | 19/103 (18) | 36/118 (31) | <0.001 |
| Calcium channel blocker | 344/537 (64) | 83/118 (70) | 94/148 (64) | 0.40 |
| ACE inhibitor | 93/524 (18) | 32/115 (28) | 46/144 (32) | <0.001 |
| ARB | 58/457 (13) | 21/99 (21) | 27/115 (23) | 0.005 |
| Diuretics | 124/537 (23) | 68 (58) | 82/148 (55) | <0.001 |
| Aspirin | 226/537 (42) | 56 (47) | 79/148 (53) | 0.042 |
| PDE5 inhibitor | 91/536 (17) | 37 (31) | 48/148 (32) | <0.001 |
| Endothelin receptor antagonist | 26/537 (5) | 19 (16) | 24/148 (16) | <0.001 |
| Prostacyclin analog | 17/537 (3) | 7 (6) | 13/148 (9) | 0.012 |
PDE5: phosphodiesterase 5 inhibitor; ERA: endothelin receptor antagonist