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. Author manuscript; available in PMC: 2023 May 1.
Published in final edited form as: Biochem Pharmacol. 2022 Apr 5;199:115012. doi: 10.1016/j.bcp.2022.115012

Table 2:

Systemic hormone receptors and their role in obesity and obesogen action

Hormone receptor Abbreviation Agonists promote:
Insulin receptor IR Increased adiposity
Estrogen receptors ER (α, β) Increased adiposity
Androgen receptor AR Decreased adiposity, lipid accumulation
Glucocorticoid receptor GR Increased adiposity
Thyroid hormone receptors TR (α, β) α- increased adiposity, increased cholesterol, triglycerides
β- reduction in cholesterol, triglycerides, and adiposity