Table 1.
Cycle characteristics and laboratory and clinical outcomes of study groups
| Total | Population groups | p-value | ||
|---|---|---|---|---|
| Vienna consensus | Older female age | |||
| ≤ 39 year | ≥ 40 years | |||
| n = 862 | n = 607 | n = 255 | ||
| Patients and cycles characteristics | ||||
| Female age (year) | 36.5 ± 4.6 | 34.3 ± 3.4 | 41.9 ± 1.6 | p < 0.001 |
| Male age (year) | 39.6 ± 5.9 | 37.7 ± 5.1 | 43.9 ± 5.1 | p < 0.001 |
| Number of total sperm | 36.4 ± 50.1 | 35.8 ± 50.6 | 38 ± 49.1 | NS |
| Number of recovered oocytes (m ± sd) | 9095 (10.6 ± 5.7) | 6861 (11.3 ± 5.8) | 2234 (8.8 ± 5.1) | p < 0.001 |
| BMI | 21 ± 3.2 | 21.9 ± 3.2 | 22.1 ± 3.4 | NS |
| Fertilization | ||||
| ICSI (%) | 72.9 | 72.3 | 75.3 | NS |
| Standard IVF (%) | 67.0 | 67.2 | 67.3 | NS |
| Embryo development | ||||
| Day 2 embryo development (%) | 57.9 | 57.6 | 58.7 | NS |
| Day 3 embryo development (%) | 52.0 | 52.4 | 50.7 | NS |
| Number of usable blastocysts (m ± sd) | 223 (2.6 ± 1.9) | 1778 (2.9 ± 2.0) | 458 (1.8 ± 1.4) | p < 0.001 |
| Total good blastocyst development rate (day 5–day 6) | 42.3 | 45.5 | 33.4 | p < 0.001 |
| Cryopreservation | ||||
| Blastocyst cryosurvival (%) | 95.0 | 95.2 | 94.2 | NS |
| Clinical results | ||||
| Implantation (%) | 28.3 | 34.3 | 16.9 | p < 0.001 |
| Cumulative clinical pregnancy (%) | 44.0 | 52.4 | 23.9 | p < 0.001 |