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Summary of whole-cell patch clamp recordings on HEK293T cells transiently transfected with wildtype or mutant rat TRPV2.
| TRPV2 variant | EC50, μM | Hill coefficient | Number of experiments |
|---|---|---|---|
| Wildtype | 322 ± 27 | 3.0 ± 0.2 | 8 |
| His521Ala | 991 ± 131 | 3.3 ± 0.3 | 8 |
| His521Asn | 742 ± 14 | 4.3 ± 0.3 | 5 |
| Arg539Lys | 683 ± 78 | 5.6 ± 1.1 | 4 |
| Arg535Lys | 79 ± 11 | 3.3 ± 0.5 | 4 |
| Thr522Ala | 232 ± 43 | 3.0 ± 0.3 | 8 |
| His521Ala/Arg539Lys | 1753 ± 125 | 5.2 ± 0.6 | 6 |
