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. 2022 Apr 28;12:6926. doi: 10.1038/s41598-022-10352-3

Table 6.

Summary of clusters and gene sets included in the pattern A for the renal IRI sex comparison.

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I-Immune cell regulation Leucocyte cell–cell adhesion
T cell differentiation and activation in immune response
TNF production
INFy production
NF-kB signaling
Toll-like receptor signaling pathway (TLR3/TLR4)
Complement cascade
II-Morphogenesis development migration Positive regulation of leucocyte chemotaxis and migration
Cellular response to chemokine
Positive regulation of mononuclear cell migration
III-Ion transport transmembrane Cytosolic calcium
Calcium transport
Positive regulation of cytosolic calcium ion concentration
IV-Apoptotic intrinsic extrinsic Intrinsic apoptotic signaling pathway
Intrinsic apoptotic signaling pathway by p53 class mediator
Regulation of signal transcription by p53
VI-Alcohol biosynthetic process Steroid biosynthetic process
Regulation of cholesterol biosynthesis by SREBP (SREBF)
Metabolism of steroids
Lipid biosynthesis and metabolism
Inositol phosphate metabolic process
Cellular ketone metabolic process
VII-Steroid hormone response Cellular response to hormone stimulus
Peptide
Estradiol
Cellular response to insulin stimulus (insulin receptor signaling pathway)
VIII-Regulation hormone secretion Regulation of peptide, protein, hormone secretion and transport by cell