Table 2.
1 | Post-infectious: typically shows spontaneous resolution over time |
2 | Airway infections (protracted/recurrent/persistent): Protracted bacterial bronchitis, chronic suppurative lung disease, bronchiectasis, cystic fibrosis, immune deficiency/ciliary dyskinesia, alpha-1 antitrypsin deficiency, other chronic infections e.g., tuberculosis and atypical mycobacteria |
3 | Airway anomaly: Primary or secondary tracheobronchomalacia, congenital airway and pulmonary malformation |
4 | Airway inflammation: Asthma, eosinophilic bronchitis, environmental pollutants |
5 | Airway aspiration: Primary airway aspiration, secondary aspiration owing to gastroesophageal reflux, foreign body aspiration |
6 | Upper airway associations: Rhinitis, sinusitis |
7 | Tic and somatic syndrome |
8 | Extra-pulmonary: Drug-induced, cardiac, vagal nerve branches stimulation (e.g., Arnold's ear reflex) |
9 | Other specific diseases associated with chronic cough: Interstitial lung disease or tumors |
*Some overlap, for example, chronic cough related to primary ciliary dyskinesia can be both infection and inflammation.