Table 1.
Demographics and clinical characteristics before and after 5 months of treatment.
| Characteristics | Before treatment (n = 105) | 5 months after treatment initiation | p -value |
|---|---|---|---|
| Age in years, media (IQR) | 32 (25–40) | - | |
| Age group in years, n (%) | |||
| 18–24 | 19 (18.1) | - | |
| 25–34 | 44 (41.9) | - | |
| 35–44 | 26 (24.8) | - | |
| ≥45 | 16 (15.2) | - | |
| Female, n (%) | 32 (30.5) | ||
| BMI, kg/m2, median (IQR) | 18.06 (16.87–19.71) | 19.76 (17.86–21.13) | <0.001 |
| HIV+, n (%) | 12 (11.4) | 13 (12.64) | |
| On ART, n (%) | 12 (100) | 13 (100) | |
| Symptoms, n (%) | |||
| Cough | 103 (98.1) | - | |
| Positive finding at lung auscultation | 93 (88.6) | - | |
| Fever | 74 (70.4) | 10 (9.5) | |
| Chest pain | 72 (68.6) | - | |
| Night sweat | 48 (45.7) | - | |
| Hemoptysis | 11 (10.5) | - | |
| Anemic conjunctivae | 6 (5.7) | - | |
| Dyspnoea | - | - | |
| BMI <18 | 51 (48.6) | 28 (26.7) | |
| BMI <16 | 13 (12.4) | 2 (1.9) | |
| MUAC <220 | 18 (9.5) | 12 (11.4) | |
| MUAC <200 | 7 (6.7) | 1 (0.9) | |
| TB patient category, n (%) | |||
| New | 101 (96.2) | - | |
| Relapse | 4 (3.8) | - | |
| Treatment after default | - | - | |
| Treatment outcome cured | na | 105 (100) | |
| Full blood counts (109 cells/L) | |||
| White blood cells, median (IQR) | 8.080 (6.310–9.750) | nd | |
| Platelets, median (IQR) | 299 (242–400) | nd | |
| Red blood cells, mean (±SD) | 4.841 (0.90) | nd | |
| Xpert MTB/RIF Ct values results | |||
| Ct values median (IQR) | 19.40 (15.90–22.60) | ||
| HIV+, Ct values median (IQR) | 25.45 (18.85–28.18) | ||
| HIV−, Ct values median (IQR) | 19.10 (15.60–22.00) | 0.04665 § | |
| Smear results, n (%) | |||
| Scanty | - | ||
| 1+ | 6 (5.7) | - | |
| 2+ | 5 (4.8) | - | |
| 3+ | 4 (3.8) | - | |
| Negative | - | 75 (71.4) | |
| Not done | 90 (85.7) | 30 (28.6) | |
BMI, Body mass index; HIV, Human immunodeficiency virus; AFB, Acid-fast bacteria; MTB, Mycobacterium tuberculosis; ART, Antiretroviral therapy; na, not applicable; nd, not done; Ct, Cycle threshold; neg, negative. Smear results, Scanty, 1-9 AFB per 100 fields; 1+, 10-99 AFB per 100 fields; 2+, 1-10 AFB per field in at least 50 fields; 3+, more than 10 AFB per field in at least 20 fields; Negative, no AFB in at least 100 fields; § Compared to HIV+ arm.