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. 2022 Apr 15;16:859298. doi: 10.3389/fnins.2022.859298

TABLE 2.

Inertial sensor-based gait and balance analysis: from the prospect of event detection, spatiotemporal parameter estimation, joint ROM, and balance analysis.

Reference Parameter(s) Technique(s) used Subject(s) Calibration/validation technique Remarks
Event detection/temporal parameter measurement
(Jasiewicz et al., 2006) HS and TO One gyroscope, two linear accelerometers, peak detection, zero crossing, heuristic 26 HC + 14 SCI + Charcot-Marie-Tooth (CMT) Foot switches TO latency 50 ms, 100 ms for HS detection; obtrusive due to semi-wired connectivity
(Raveendranathan et al., 2011) HS and HO Single 3-axis accelerometer at alternate/multiple positions; peak detection + HMM 1 HC None Adaptive to Sensor placement
(Yang et al., 2012) HS and asymmetry feature Single accelerometer placed at the lower back, peak detection 15 HC N/A No specific accelerometer; The developed iGAIT tool requires manual intervention to set input pre-sets
(Mariani et al., 2013) HS, TO, HO, and TS Foot mounted 3D accelerometer+ gyroscope, pitch velocity, negative peak, zero crossing 10 HC, 12 AO, 11 TAR, and 9 AA Pedar-X Pressure Insole −33 ± 14 for angular velocity, 81 ± 15 for acceleration
(Hundza et al., 2013) Temporal, stride length 4 IMU (gyroscope), Y-angular rate reversal 6 (PD) + 7 (HC) GAITRite, OMC 100% event detection, SD of 6.6 ms and 11.8 ms in HC and PD
(Joshi et al., 2016) TO Three-axis accelerometer, wavelet decomposition 6 HC Foot switch The transition between level ground and ramps
(Das et al., 2019) HS and TO Six-axis IMU, Foot angle variation, peak detection 34 HC FSR Improved detection latency of 16 ms
Joint kinematics and ROM
(Dejnabadi et al., 2005) Knee angle One IMU (Two accelerometer + one gyro) placed at shank and thigh; virtual projection of physical sensor into rotation joint 8 HC OMC Absolute angle calculation with no drift error; subject-specific modeling requires prior anatomical information
(Dorschky et al., 2019) Hip, knee, and ankle angle 07 six-axis IMU, musculoskeletal model, trajectory optimization 10 HC (M) OMC P ≥ 0.93
(Gholami et al., 2020) Hip, knee, and ankle flexion/extension 01 accelerometer placed at foot + CNN 10 HC (M) OMC RMSE <3.4% for intra-subject and <6.5% for inter subject
Spatiotemporal parameters
(Salarian et al., 2012) HS, TO, SL, and gait velocity Two gyroscopes placed at the shank, a Double pendulum model with two gyroscopes + Fourier series, and most minor square optimization 10 PD, 18 HC, 36 hip-replacement, and seven orthosis OMC Validated on a sizeable patient population with multiple disorders
(Takeda et al., 2014) Gait phases, SL, and LStep One IS on each ankle, shank, and thigh; one on the pelvis. Peak detection for events, drift reduction protocol for spatial parameters 5 HC, 10 m walk-test OMC Linear drift modeling does not hold for extended walking
(Rampp et al., 2015) SL, GCT, Tswing, and Tstance Inertial sensors, Template Search for events 101 NW, 84 WW GAITRite® 0.93 and 0.95 in NW and 0.80 and 0.95 in WW for SL and GCT, respectively
(Wang and Ji, 2015) Tstance, Tswing, and SL Foot mounted IS, peak-peak detection+ adaptive thresholding for event detection; CF+ ZUPT+ double integration for SL 15 HC Non-standard 1.64 ± 0.839 for SL
(Liu et al., 2016) SL 3D acceleration and angular rate, Dual-ZUPT 14 steps Videography
(Ferrari et al., 2015) GCT, SL, and stride velocity Foot mounted IMU, Medial-lateral foot angle peak detection for events; KF+ZUPT for stride length 12 HC, 16 PD GAITRite® Real-time computation on a smartphone, RMSE SL = 4%
(Hao et al., 2019) SL 3D Euler angle, acceleration, discrete KF, smoother 9 HC (male adults) OMC −0.24 ± 1.1 cm for SL
(O’brien et al., 2019) Tstance, TSw, SL, step velocity, and step count One IMU at hip; Local minima/maxima + Butterworth filter for events; IPM + Double integration for SL 51 HC GAITRite® Need for additional optimization constant that is derived from GAITRite® for SL estimation
(Das and Kumar, 2021) SL Six-axis IMU at foot dorsum; foot angle for gravity compensation and double integration of foot acceleration 10 HC Zebris walkway, outdoor marking Acceleration integrated only for swing duration; compensated with foot length
Spatiotemporal + Joint kinematics
(Teufl et al., 2019a) 12 STP including Lstp, step width, 6 DoF kinematics 7 Xsens IS 24 HC (12 M + 12 F) OMC Detection means error ∼1.6%, Step width, and swing width RMSE > 30%
(Yeo and Park, 2020) Stt, SL, cadence, step length; knee and hip ROM Five triaxial accelerometers, gyroscope, and magnetometer (LEGSys+ wearable device) placed at shank, thigh, and pelvis; self-selected walking at the 7-m walkway 30 HC OMC The significant difference in hip ROM; measurement within 95% limit of agreement
Balance
(Hsu et al., 2014) CoM, postural sway rate Three-axis accelerometer in waist 21 PD + 50 HC N/A Validated on a large group; Only static balance
(Wang W.-H. et al., 2015) TUGT Three IMUs (1 at hip + 1 at each foot); Signature matching of lateral angular rate + thresholding 21 AD + 25 HC N/A Test specific
(O’brien et al., 2019) 10 MWT, BBS, and TUGT One IMU at hip; FFT+ integration for static balance; Daubechies wavelet approximation for dynamic balance 51 HC GAITRite® 178 features extracted for three balance assessment tests
(Noamani et al., 2020) Two minutes standing test, inter-segmental moments, and CoP Accelerometer + gyroscope placed at foot, leg, pelvis, and head-arms-trunk; Musculoskeletal inverse dynamics model 10 HC OMC+ force plates Accelerometers alone provide reliable data for standing balance analysis
(Dugan et al., 2021) Two minutes barefoot standing in EO, EC 17 IMU placed at whole body; jerk index and complexity index from postural sway from pelvis accelerometer 38 concussed patients N/A Single accelerometer yields information about postural sway

HS, heel strike, TO, toe off, HC, healthy control, SCI, spinal cord injury, CMT, Charcot-Marie-Tooth, HMM, Hidden Markov Model, HO, heel off, TS, toe strike, AO, ankle orthosis, TAR, total ankle replacement, AA, ankle arthrodesis, OMC, optical motion camera, CNN, convolution neural network, CF, complementary filter, ZUPT, zero update, KF, Kalman Filter, GCT, Gait cycle time, IPM, inverted pendulum model, Stt, stance time, TSw, swing time, Lstp, step length, CoM, center of Mass, TUGT, time-up and go test, 10 MWT, 10 meter walk test, BBS, Berg Balance Scale, AD, Alzheimer’s disease, FFT, Fast Fourier transform.