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. 2022 Apr 15;13:775186. doi: 10.3389/fmicb.2022.775186

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Copyright © 2022 Schwedler, Grzeski, Kappert, Rust, Heymann, Hoppe and Blanchard.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Representative MALDI-TOF-mass spectra [M-H]^– of (A) total IgG_1/2 and (B) anti-Spike IgG₁ isolated from plasma of severe COVID-19 patient (male, age 51) at beginning (day 6), midpoint (day 18), and the end (day 31) of the disease. IgG₁ glycopeptides are marked in red and IgG₂ glycopeptides are marked in black.