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. 2022 May;63(5):761–769. doi: 10.2967/jnumed.121.262610

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© 2022 by the Society of Nuclear Medicine and Molecular Imaging.

Immediate Open Access: Creative Commons Attribution 4.0 International License (CC BY) allows users to share and adapt with attribution, excluding materials credited to previous publications. License: https://creativecommons.org/licenses/by/4.0/. Details: http://jnm.snmjournals.org/site/misc/permission.xhtml.

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FIGURE 4. — Simulation results and graphical explanation. (A) DSB-yield (DSBs/Gbp SP) comparison for the 3 cell morphologies (as indicated by x-axis), the 3 source localizations (Cy, G [including contribution of CM], and medium), and the 2 emission types. Medium contribution is assumed to be same for the 3 morphologies on basis of simulations for cell 1. (B) Total nucleus irradiation (i.e., self- and cross-irradiation) characterizing nucleus 3 when IC electrons are emitted from G. (C) Total nucleus irradiation (i.e., self- and cross-irradiation) characterizing nucleus 1 when IC electrons are emitted from G. Color bars indicate energy (keV) at entrance of nucleus.