TABLE 2.
90Y-FAPI-46 Administered Activity and Absorbed Doses Per Cycle
| Patient no. | Cycle no. | Activity (GBq) | Radiation dose (Gy/GBq) | ||||
|---|---|---|---|---|---|---|---|
| Tumor lesion 1 | Tumor lesion 2 | Kidney | Liver and lung* | Bone marrow | |||
| 1 | 1 | 7.1 | 0.74 | 0.63 | — | — | — |
| 2 | 1 | 7.0 | — | — | — | — | — |
| 3 | 1 | 3.5 | 1.23 | 1.23 | 0.75 | <0.18 | 0.06 |
| 2 | 7.3 | 1.28 | 0.95 | 0.41 | <0.19 | 0.04 | |
| 3 | 7.5 | 1.47 | 1.35 | 0.61 | <0.15 | 0.04 | |
| 4 | 1 | 3.8 | — | — | — | — | — |
| 5 | 1 | 3.8 | — | — | — | <0.16 | 0.06 |
| 6 | 1 | 3.0 | 1.37 | — | — | — | — |
| 7 | 1 | 3.5 | 0.91 | 0.84 | 0.52 | <0.16 | 0.03 |
| 8 | 1 | 3.8 | 0.49 | — | 0.11 | <0.26 | 0.08 |
| 2 | 7.4 | — | — | — | — | 0.08 | |
| 9 | 1 | 2.6 | 2.28 | — | 0.65 | <0.21 | 0.04 |
| 2 | 7.4 | 1.79 | — | 0.45 | <0.25 | 0.02 | |
| Median | 1.28 | 0.95 | 0.52 | <0.19 | 0.04 | ||
| IQR | 0.83–1.71 | 0.74–1.32 | 0.41–0.65 | <0.16–0.24 | 0.04–0.07 | ||
*
Estimation based on maximum detectable activity concentration and blood tracer kinetic.