Spirooxindoles obtained with pre-synthesized acyl chloride^a.

Compound #	R1	R2	R3	a/b	Yield,%
22a,b	H	4F	4-Cl	1/2	64
23a,b	H	4-Cl	4-Cl	1/2	53
24a,b	H	4-Br	4-Cl	1/2	49
25a,b	H	4-OH	4-Cl	1/2	62
26a,b	H	4-OEt	4-Cl	1/5	57
27a,b	H	3-Cl, 4-F	4-Cl	2/5	55
28b	H	2-F	4-Cl	—	44

^aReaction conditions: Schiff base (1.0 eq.), 4-chlorophenylacetyl chloride (1.5 eq.), Et₃N (3.0 eq.), DMF, reflux for 6–9 h.