The structure and anti-MTB activity of new BTZs series 1.

Compd	R	MIC (μM)	Compd	R	MIC (μM)
1		0.462	17	m-NO2	0.414
2	p-F	0.244	18	m-CF3	0.101
3	p-Cl	1.654	19	m-MeO	3.671
4	p-Br	0.953	20	o-F	3.595
5	p-CN	0.616	21	p-F, m-F	0.111
6	p-NO2	0.451	22	p-Cl, m-Cl	0.077
7	p-CF3	0.112	23	p-F, m-Cl	0.104
8	p-MeO	1.832	24	p-Cl, m-F	<0.035
9	p-tBu	0.218	25	p-F, o-Cl	0.888
10	p-Me	1.926	26	p-F, o-F	0.232
11	p-CF3O	<0.035	27	p-Cl, o-Cl	0.566
12	H	0.796	28	p-F, o-Br	0.783
13	m-F	0.222	PBTZ169		<0.035
14	m-Cl	0.217	INH		0.262
15	m-Br	0.203	RFP		0.166
16	m-CN	0.223