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. 2022 Apr 29;12(4):e752. doi: 10.1002/ctm2.752

FIGURE 12.

FIGURE 12

A schematic model of LINC01606–SCD1–Wnt/β‐catenin signalling circuit in colon cancer cells. LINC01606 activates Wnt/β‐catenin signalling by SCD1, promoting cancer cell growth and stemness and inhibiting ferroptosis. Simultaneously, activating Wnt/β‐catenin signalling in turn enhances LINC01606 expression by TFE3, forming a LINC01606–SCD1–Wnt/β‐catenin signalling circuit