MICs of the synthesized compounds against Gram-negative bacteria strains (μg mL⁻¹).

	Bacterial strains
	E. coli ATCC 25922	E. coli ATCC 8739	E. coli ATCC BAA-2469a	K. pneumoniae ATCC BAA-2470a	A. baumannii ATCC 19606b	P. aeruginosa ATCC BAA-2108b	E. cloacae ATCC BAA-1143c
4a1	2	4	8	32	64	64	>64
4a2	4	8	4	64	64	64	64
4a3	4	4	4	32	64	64	>64
4a4	0.5	1	1	8	16	64	64
4b1	2	8	1	32	64	64	>64
4b2	4	4	2	32	64	64	>64
4b3	2	4	4	32	64	64	>64
4b4	2	2	0.5	8	16	16	>64
4c1	8	64	64	>64	>64	>64	>64
4c2	4	32	8	>64	>64	>64	>64
4d1	4	16	4	16	32	32	64
4d2	32	32	16	>64	>64	>64	>64
4d3	16	32	32	64	64	64	>64
4e1	16	32	16	64	>64	>64	>64
4e2	4	16	8	64	>64	64	>64
4e3	16	32	16	64	64	32	64
4e4	16	16	8	32	>64	64	64
ampd	1	2	>64	>64	64	>64	>64
vand	>64	>64	>64	>64	64	>64	>64
methd	2	>64	>2048	>2048	>256	>64	>96
rifd	4	8	>64	>64	1	>64	64

^aNDM-1 expressing strain, which is resistant to most of the antibiotics, except tigecycline and colistin.

^bMulti-drug resistant strain.

^cAmpC beta-lactamase expressing strain.

^damp: ampicillin; van: vancomycin; meth: methicillin; rif: rifampin.