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. 2022 Apr 29;19:104. doi: 10.1186/s12974-022-02465-3

Table 2.

Effects of high fat diet consumption on the metabolic hormones of WT or TLR4-mut mice

Metabolic hormones (pg/mL) WT TLR4-mut
ND HFD ND HFD
Leptin 2323 ± 166 3302 ± 407 1868 ± 777 2535 ± 312
Resistin 4730 ± 499 8649 ± 145 3221 ± 499 4495 ± 517#
Glucagon 11.9 ± 0.2 7.3 ± 0.9 6.5 ± 1.0 5.1 ± 0.7
Ghrelin 6.9 ± 0.3 11.2 ± 1.9* 8.5 ± 0.5 8.20 ± 0.8
GIP 220 ± 19 430 ± 134* 211 ± 44 237 ± 45

GIP glucose-dependent insulinotropic polypeptide. Values represent the mean ± SEM of 8–12 animals per group. *p < 0.05 vs. WT-ND and #p < 0.05 versus WT-HFD