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. 2022 Apr 29;20:137. doi: 10.1186/s12957-022-02588-0

Table 2.

Relationship between SIRI and clinical variables

Clinical variables Original cohort PSM cohort
SIRI < 1.26 (n = 177) SIRI ≥ 1.26 (n = 114) p value SIRI < 1.26 (n = 98) SIRI ≥ 1.26 (n = 98) p value
Age at diagnosis < 55 94 55 0.933 50 46 0.988
≥ 55 83 59 48 52
Gender Male 96 90 < 0.001 73 74 0.177
Female 81 24 25 24
Preoperative seizure Yes 25 15 0.83 15 13 0.974
No 152 99 83 85
KPS ≤ 80 103 80 0.396 59 64 0.959
> 80 74 34 39 34
Hemisphere Right 74 58 0.11 43 46 0.465
Left 94 50 51 47
Midline or bilateral 9 6 4 5
Tumor location Frontal lobe 70 28 0.088 32 28 0.136
Temporal lobe 29 30 16 27
Parietal lobe 20 6 12 6
Occipital lobe 6 2 1 2
Insular lobe 7 5 5 5
Other regions 45 43 32 30
Ki-67 index < 30% 105 65 0.636 63 56 0.217
≥ 30% 72 49 35 42
IDH-1 status Mutant 29 13 0.531 15 12 0.491
Wildtype 148 101 83 86

Significant findings are expressed in bold and italic

Abbreviations: KPS Karnofsky performance status, IDH-1 isocitrate dehydrogenase-1, SIRI systemic inflammation response index, NLR neutrophil to lymphocyte ratio, PSM propensity score matching