Table 2.
Clinical variables | Original cohort | PSM cohort | |||||
---|---|---|---|---|---|---|---|
SIRI < 1.26 (n = 177) | SIRI ≥ 1.26 (n = 114) | p value | SIRI < 1.26 (n = 98) | SIRI ≥ 1.26 (n = 98) | p value | ||
Age at diagnosis | < 55 | 94 | 55 | 0.933 | 50 | 46 | 0.988 |
≥ 55 | 83 | 59 | – | 48 | 52 | – | |
Gender | Male | 96 | 90 | < 0.001 | 73 | 74 | 0.177 |
Female | 81 | 24 | – | 25 | 24 | – | |
Preoperative seizure | Yes | 25 | 15 | 0.83 | 15 | 13 | 0.974 |
No | 152 | 99 | – | 83 | 85 | – | |
KPS | ≤ 80 | 103 | 80 | 0.396 | 59 | 64 | 0.959 |
> 80 | 74 | 34 | – | 39 | 34 | – | |
Hemisphere | Right | 74 | 58 | 0.11 | 43 | 46 | 0.465 |
Left | 94 | 50 | 51 | 47 | – | ||
Midline or bilateral | 9 | 6 | – | 4 | 5 | – | |
Tumor location | Frontal lobe | 70 | 28 | 0.088 | 32 | 28 | 0.136 |
Temporal lobe | 29 | 30 | – | 16 | 27 | – | |
Parietal lobe | 20 | 6 | – | 12 | 6 | – | |
Occipital lobe | 6 | 2 | – | 1 | 2 | – | |
Insular lobe | 7 | 5 | – | 5 | 5 | – | |
Other regions | 45 | 43 | – | 32 | 30 | – | |
Ki-67 index | < 30% | 105 | 65 | 0.636 | 63 | 56 | 0.217 |
≥ 30% | 72 | 49 | – | 35 | 42 | – | |
IDH-1 status | Mutant | 29 | 13 | 0.531 | 15 | 12 | 0.491 |
Wildtype | 148 | 101 | – | 83 | 86 | – |
Significant findings are expressed in bold and italic
Abbreviations: KPS Karnofsky performance status, IDH-1 isocitrate dehydrogenase-1, SIRI systemic inflammation response index, NLR neutrophil to lymphocyte ratio, PSM propensity score matching