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. 2022 Apr 28;20:189. doi: 10.1186/s12967-022-03392-w

Table 2.

Exosomes as diagnostic, prognostic or predictive biomarker in solid tumor

Exosomes/Exosomal contents Cancer types Specimen origin Biomarker function References
Exosome circMYC NPC Serum Differentiate radioresistant patients from patients with radiosensitive NPC [38]
Exosome miR-339-5p ESCC Serum Predict radiotherapeutic response [46]
Exosome miR-96 NSCLC Plasma Diagnostic and prognostic marker of radioresistant NSCLC [50]
Exosome miR-378 NSCLC Serum Predict radiotherapeutic response [51]
Exosome miR-29a-3p miR-150-5p NSCLC Serum Predict radiotherapeutic response; radiation-related [52]
Exosome HSP70 NSCLC Plasma Predict radiotherapeutic response [55]
Exosome miR-663a CRC Plasma Predict radiotherapeutic response [67]
Exosome miR-574-3p Glioblastoma Serum Predict radiotherapeutic response [85]
Exosome miR-379-5p miR-654-3p Prostate cancer Serum Predict radiotherapeutic response [91]
Exosome proteome Breast cancer Body fluids Differentiate radiation-resistant tumors [99]