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. 2022 Apr 28;14:57. doi: 10.1186/s13148-022-01272-0

Fig. 4.

Fig. 4

Epigenetic mutation load (EML) in preterm infants with or without bronchopulmonary dysplasia (BPD). EML was significantly higher in BPD samples than in non-BPD samples. EML was calculated as the natural log (ln) of total number of stochastic epigenetic mutations (SEMs) per individual. In violin-plot, green dot and bar show mean and standard deviation, respectively. *Statistics of linear regression on EML; r = 0.39, p = 4.18 × 10–5 (p adjusted = 0.02). Statistics of biweight midcorrelation (bicor); r = 0.32, p = 6.56 × 10–4